Hans Christian Gram was a Danish scientist who developed the gram bacteria stain that is used in classifying bacteria.
Tuesday 10 March 2015
Seminar begins at 4pm in S012
(cookies at 3:30)
Title to be determined
Dr. Jeong-Ho Kim
Department of Biochemistry and Molecular Medicine
George Washington University Medical Center
Dr. Kim research is gaining insights into the elevated rate of glycolysis observed in many solid tumors, the laboratory is investigating the underlying mechanism of aerobic glycolysis using the yeast as a genetic model. Distinguishing features of aerobic glycolysis are increased glucose uptake and decreased respiratory activity. Such metabolic changes are caused by reprogramming of their transcriptome in response to glucose, largely mediated by two glucose signaling pathways - the Rgt/Snf3 glucose induction pathway, which is also responsible for expression of the glucose transporter genes and the Snf1-Mig1 glucose repression pathway which in-turn leads to repression of the respiratory genes. We are interested in understanding how glucose sensing and signal transduction occur at the cell surface.
For more information visit Dr. Kim's Laboratory at http://www.gwumc.edu/smhs/facultydirectory/profile.cfm?empName=Jeong-Ho%20Kim&FacID=2076630771